Accuracy Of Fine Needle Aspiration Cytology In Diagnosis Of Thyroid Swelling
Accuracy of FNAC in Diagnosis of Thyroid Swelling
Keywords:
Accuracy, Fine Needle Aspiration Cytology (FNAC), thyroidAbstract
Fine needle aspiration cytology is a well established, safe and out patient procedure used in diagnosis of thyroid swelling. Aims: The aim of this study is to determine the accuracy of FNAC in detection of thyroid lesions at our institute. Material and methods: 100 cases of thyroid swelling were diagnosed and treated at M.P.Shah medical college, Jamnagar from Jan1997 to May 1998. FNAC results were compared with final histopathological diagnosis. FNA results were classified as inadequate material, non-neoplastic, neoplastic and malignant lesions. Results: FNA analysis showed 74.19%(69 cases) non-neoplastic lesion, 19.35%(18cases) neoplastic lesion and 6.45%(6cases) malignant lesion. Histopathological analysis showed 70.18%(40) non-neoplastic lesion and 29.83%(17) neoplastic lesion – 15.79%(9) adenomas and 14.04%(8) carcinomas. Conclusions: The accuracy rate of FNAC in diagnosis for non-neoplastic, neoplastic and malignant lesions were 90.91%,100% and 100% espectively. So, overall accuracy of FNA in present study was 92.98%.
References
1. Gutman PD, Henrt M. Fine needle aspiration cytology of thyroid. Clinics in Lab Medicine, 1998,18:461-482.
2. Campbell JP, Pillsbury HC.Management of thyroid nodule. Head Neck 1989,11:414-425.
3. Reeve D, Delbridge L, Sloan D, Crummer P. The impact of fine needle biopsy on surgery for single thyroid nodule. Med J Aust 1986, 145:308-311.
4. Caruso P, Muzzaferri EL. Fine needle aspiration biopsy in the management of thyroid nodules. Endocrinology 1991, 1:194-202.
5. Frable William J. thin needle aspiration biopsy. A personal experience with 469 cases. Am. J. Clin. Pathol. 1976, 65:168-182.
6. Christopherson William. M. cytologic detection and diagnosis cancer. Its contribution and limitation. Cancer 1983,51:1201-1208.
7. Miller JM, Kini SR, Hamberg JI. The needle biopsy diagnosis of papillary thyroid carcinoma. Cancer1985, 55:2812-2817.
8. B. Mundasad, I. Mcallister, J. Carson, P. C. Pyper. Accuracy of fine needle aspiration cytology in diagnosis of thyroid swellings. The internet Journal of endocrionology. 2006.Vol. 2 Mo. 2.
9. Baloch ZW, Sack MJ, Yu GH, Livolsi VA, Gupta PK. Fine needle aspiration of thyroid: an institutiona experience. Thyroid 1998, 8:565-569.10. Boyd CA, Eamhardt RC, Dunn JT, Frierson HF, Hanks JB. Pre operative evalution and predictive value of fine needle aspiration and frozen section of thyroid nodules. J Am Coll Surg 1998, 187:494-502.
11. Layfield LJ, Reichman A, Bottles K, Giuliano A. Clinical determinants for the management of thyroid nodules by fine needle aspiration cytology. Arch Otolary Head Neck Surg. 1992, 118:717-721.
12. Silverman JF, West RL, Ernest W, Park KH, Finely JL, Swanson MS, Fore WW. The role of FNAB in the rapid diagnosis and management of thyroid neoplasm. Cancer 1986, 57:1164-1170.
13. Sirpal YM. Efficacy of FNAC in the management of thyroid disease. Ind. J. Pathol & Microbiol 1996, 39(3).
14. Suen Kenneth C, Quenville NF. FNAB of the thyroid gland. A study of 304 cases. J. Clin. Pathol. 1983, 36:1036-1045.
15. Dorairajan N, Jayshree N. Solitary nodule of the thyroid and the role of FNAC in diagnosis. J. Ind. Med. As. 1996, 94(2):50-52.
16. Caraway NP, Snoege N, Samaan NA. Diagnostic pit falls in thyroid fine needle aspiration: a review of 394 cases. Diag Cytopathology. 1993, 9:345-350.
17. Burch HB, Burman KP, Reed HL, Buckner L, Raber T, Owenbey JL. Fine needle aspiration biopsy of thyroid nodule: determinants of insuffiency rate and malignancy yield at thyroidectomy. Acta Cyto. 1996, 40:1176-1183.
18. Gharib H, Goellner JR, Johnson DA. fine needle aspiration cytology of the thyroid: a 12 year experience with 11000 biopsies. Clin Lab Med.1993, 13:699-709.
19. Caplan RH, Strutt PJ, Kisken WA. FNAB of thyroid nodules. Wisconsin Med. J. 1991, 90:285.
20. La Rosa GL, Belfiore A, Giuffrida D. Evaluation of the FNAB in the pre-operative selection of cold thyroid nodules Cancer1991,67:2137.
21. Layfield LJ, Mohrmann RL, Kopald KH. Use of aspiration cytology and frozen section examination for management of benign and malignant thyroid nodules. Cancer 1991, 68:130.
22. Klemi PJ, Joensou H, Nylamo E. FNAB in the diagnosis of thyroid nodules. Acta Cytol. 1991, 35:434.
23. Piromalli D, Martelli G, Del PI. The role of FNA in the diagnosis of thyroid nodules. Analysis of 795 consecutive cases. J. Surg. Oncol. 1992, 50:243.
24. Fon LJ, Deans GT, Lioe TF et al. An audit of thyroid surgery in a general surgical unit. Ann R Coll Surg Eng 1996, 78:192-196.
25. Giuseppe A, Maria P, Italo N. Fine needle aspiration cytology of thyroid gland disease. The international Academy of cytology March-april 1990, vol 34, No 2.
26. Cap J, Ryska A, Rehorkova P, Hovorkova E, Kerekes Z, Pohnetelova D. Sensitivity and specificity of fine needle needle aspiration biopsy of the thyroid: clinical point of view. Clinical endocrinology 1999, 51:509-515p
27. Holleman F, Hoekstra JB, Ruitenberg HM. Evaluation of fine needle aspiration cytology in the diagnosis of thyroid nodules. Cytopathology. 1995, 6:175-186.
28. Sable MS, Staren ED, Gianakakis LM, Suri D, Prinz RA. Use of FNAB and frozen section examination for management of solitary thyroid nodules. Am. Endocrinol. Surg.1997, 122(6): 1021-1030.
29. Clark OH,Quan YH, Siperstein AE., Surg. Clin. North Am. Endocrine Surgery June 1995, 75( 3).
2. Campbell JP, Pillsbury HC.Management of thyroid nodule. Head Neck 1989,11:414-425.
3. Reeve D, Delbridge L, Sloan D, Crummer P. The impact of fine needle biopsy on surgery for single thyroid nodule. Med J Aust 1986, 145:308-311.
4. Caruso P, Muzzaferri EL. Fine needle aspiration biopsy in the management of thyroid nodules. Endocrinology 1991, 1:194-202.
5. Frable William J. thin needle aspiration biopsy. A personal experience with 469 cases. Am. J. Clin. Pathol. 1976, 65:168-182.
6. Christopherson William. M. cytologic detection and diagnosis cancer. Its contribution and limitation. Cancer 1983,51:1201-1208.
7. Miller JM, Kini SR, Hamberg JI. The needle biopsy diagnosis of papillary thyroid carcinoma. Cancer1985, 55:2812-2817.
8. B. Mundasad, I. Mcallister, J. Carson, P. C. Pyper. Accuracy of fine needle aspiration cytology in diagnosis of thyroid swellings. The internet Journal of endocrionology. 2006.Vol. 2 Mo. 2.
9. Baloch ZW, Sack MJ, Yu GH, Livolsi VA, Gupta PK. Fine needle aspiration of thyroid: an institutiona experience. Thyroid 1998, 8:565-569.10. Boyd CA, Eamhardt RC, Dunn JT, Frierson HF, Hanks JB. Pre operative evalution and predictive value of fine needle aspiration and frozen section of thyroid nodules. J Am Coll Surg 1998, 187:494-502.
11. Layfield LJ, Reichman A, Bottles K, Giuliano A. Clinical determinants for the management of thyroid nodules by fine needle aspiration cytology. Arch Otolary Head Neck Surg. 1992, 118:717-721.
12. Silverman JF, West RL, Ernest W, Park KH, Finely JL, Swanson MS, Fore WW. The role of FNAB in the rapid diagnosis and management of thyroid neoplasm. Cancer 1986, 57:1164-1170.
13. Sirpal YM. Efficacy of FNAC in the management of thyroid disease. Ind. J. Pathol & Microbiol 1996, 39(3).
14. Suen Kenneth C, Quenville NF. FNAB of the thyroid gland. A study of 304 cases. J. Clin. Pathol. 1983, 36:1036-1045.
15. Dorairajan N, Jayshree N. Solitary nodule of the thyroid and the role of FNAC in diagnosis. J. Ind. Med. As. 1996, 94(2):50-52.
16. Caraway NP, Snoege N, Samaan NA. Diagnostic pit falls in thyroid fine needle aspiration: a review of 394 cases. Diag Cytopathology. 1993, 9:345-350.
17. Burch HB, Burman KP, Reed HL, Buckner L, Raber T, Owenbey JL. Fine needle aspiration biopsy of thyroid nodule: determinants of insuffiency rate and malignancy yield at thyroidectomy. Acta Cyto. 1996, 40:1176-1183.
18. Gharib H, Goellner JR, Johnson DA. fine needle aspiration cytology of the thyroid: a 12 year experience with 11000 biopsies. Clin Lab Med.1993, 13:699-709.
19. Caplan RH, Strutt PJ, Kisken WA. FNAB of thyroid nodules. Wisconsin Med. J. 1991, 90:285.
20. La Rosa GL, Belfiore A, Giuffrida D. Evaluation of the FNAB in the pre-operative selection of cold thyroid nodules Cancer1991,67:2137.
21. Layfield LJ, Mohrmann RL, Kopald KH. Use of aspiration cytology and frozen section examination for management of benign and malignant thyroid nodules. Cancer 1991, 68:130.
22. Klemi PJ, Joensou H, Nylamo E. FNAB in the diagnosis of thyroid nodules. Acta Cytol. 1991, 35:434.
23. Piromalli D, Martelli G, Del PI. The role of FNA in the diagnosis of thyroid nodules. Analysis of 795 consecutive cases. J. Surg. Oncol. 1992, 50:243.
24. Fon LJ, Deans GT, Lioe TF et al. An audit of thyroid surgery in a general surgical unit. Ann R Coll Surg Eng 1996, 78:192-196.
25. Giuseppe A, Maria P, Italo N. Fine needle aspiration cytology of thyroid gland disease. The international Academy of cytology March-april 1990, vol 34, No 2.
26. Cap J, Ryska A, Rehorkova P, Hovorkova E, Kerekes Z, Pohnetelova D. Sensitivity and specificity of fine needle needle aspiration biopsy of the thyroid: clinical point of view. Clinical endocrinology 1999, 51:509-515p
27. Holleman F, Hoekstra JB, Ruitenberg HM. Evaluation of fine needle aspiration cytology in the diagnosis of thyroid nodules. Cytopathology. 1995, 6:175-186.
28. Sable MS, Staren ED, Gianakakis LM, Suri D, Prinz RA. Use of FNAB and frozen section examination for management of solitary thyroid nodules. Am. Endocrinol. Surg.1997, 122(6): 1021-1030.
29. Clark OH,Quan YH, Siperstein AE., Surg. Clin. North Am. Endocrine Surgery June 1995, 75( 3).
Downloads
Published
2012-12-31
How to Cite
Patel, D. M., Shah, D. P., Goswami, D. H., Gonsai, R. N., Shah, D. S., & Patel, D. A. (2012). Accuracy Of Fine Needle Aspiration Cytology In Diagnosis Of Thyroid Swelling: Accuracy of FNAC in Diagnosis of Thyroid Swelling. National Journal of Integrated Research in Medicine, 3(5), 124–129. Retrieved from https://www.nicpd.ac.in/ojs-/index.php/njirm/article/view/2114
Issue
Section
Original Articles
