Changing Spectrum Of Complications In Plasmodium Vivax Malaria
Changing Spectrum Of Complications In Plasmodium Vivax Malaria
Keywords:
Plasmodium vivax, complications, thrombocytopenia, renal failureAbstract
Aims: To study the incidence and outcome of complications in Plasmodium vivax. Material and methods: An analysis of smear positive Plasmodium vivax patients admitted to Civil Hospital, Ahmedabad from July2007 to September 2007 was done. Results: There were 118 cases of malaria: Plasmodium vivax only in 23 cases (19.4%), 1 was mixed infection and 94 were Plasmodium falciparum only. Out of the 23 vivax cases , thrombocytopenia was seen in 22 cases (95.6%), hepatitis and jaundice seen in 7 cases (30.4%), and acute renal failure in 5 (21.7%). Death occurred in 2 (8.6%) and 20 (86.9%) patients recovered. The study included 19 adult patients and 4 pediatric cases. Conclusions: Plasmodium vivax can cause thrombocytopenia , jaundice, acute renal failure all of which occurs more commonly in Plasmodium falciparum. The study intends to highlight that Plasmodium vivax can also cause grave systemic complications but prognosis is favorable if early referral and timely supportive treatment is given.
References
2. Meenal Jain, Manmohan Kaur. Comparative study of microscopic detection methods and
haematological changes in malaria. IJPM 2005, 48(4):464-468.
3. SitprijaV.Nephropathy in falciparum malaria. Kidney Int 1988;34:867-77.
4. Elam-ong S, Sitprija V. Falciparum malaria and kidney: A model of inflammation. Am J Kid Dise 1998(32):361-375.
5. Transactions of Royal Soc Trop Med Hygiene. 1986: vol 80 Supplement) 3-12
6. Makkar R.P.S, Mukhopadhyay S, Monga A, Gupta A.K. Plasmodium vivax malaria presenting with severe thrombocytopenia. Brazilian J Infect Dis 2002; 6:236- 40.
7. Martello O.J Smoller M, Saladin T.A Malaria in American Soldiers. Arch Int Med 1969, 123: 383-87
8. Hartmann R.D, Dietrich M, Blenzle U, Rascho H. Malaria induced thrombocytopenia. Blood 1991( 42) : 157- 64.
9. Jadhav UM, Patkar VS, Kadam NN. Thrombocytopenia in Malaria – Correlation with Type and Severity Malaria. JAPI. Aug 2004 (52) 615 – 618.
10. Hill G.J., Knight V, Jerrery GM. Thrombocytopenia in Vivax Malaria. Lancet 1964; I:240-241.
11. Bhalla A, Suri V, Singh V. Malarial hepatopathy. J Postgrad Med 2006;52:315-20
12. Prakash J, Singh AK, Kumar NS, Saxena RK. Acute Renal Failure in Plasmodium vivax Malaria. JAPI. March 2003 ; ( 51) : 265-267.
13. Ahmad SH, Danish T, Faridi MM, Ahmad AJ, Fakhir S, Khan AS. Renal function in acute malaria in children. J Trop Pediatr 1989;35:291-294.
14. Mohapatra MK, Padhiary KN, Mishra DP, Sethy G. Atypical manifestations of P.vivax malaria. Indian J Malariol; 2002;39(1-2):18-25.
