Usefulness of Tru-Cut biopsy in the diagnosis of breast lesions
Usefulness of Tru-Cut biopsy in the diagnosis of breast lesions
Keywords:
Breast lesions, Benign, Malignant, Tru cut biopsy, HistopathologyAbstract
Introduction: Breast cancer is the most common malignant lesion in women. Tru-cut biopsy (TCB) is an accurate, reliable and a safe method of establishing the diagnosis in patients with breast lesions.
Aim: The study was undertaken toassess the diagnostic accuracy of TCB in breast lesions.
Material and Methods: A histopathological study was carried out on fifty-five patients who had undergone TCB of breast masses at Sheth L.G. General Hospital, AMC MET Medical College, Ahmedabad, Gujarat, India, from June- 2016 to May- 2018. The lesions were categorized & exact diagnosis was rendered whenever possible. Comparative statistical analysis was made between TCB specimens &post operative histopathology specimens whenever available.
Results: Total 55 TCB cases were studied; of which 32 were benign and 15 were malignant. One case fell into
atypical / indeterminate category & two cases fell in suspicious malignant category. Five TCBs were inadequate for reporting. Amongst the benign category, fibroadenoma& amongst the malignant category, invasive ductal carcinoma, not otherwise specified type were the predominant lesions. In malignant lesions gradation, 85.7% agreement was found between TCB &post operative histopathology specimens. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) & accuracy of TCBs were 83.3%, 100%, 100%, 91.4% and 94%, respectively.
Conclusion: TCB can be used as the initial investigation of choice for pre-operative diagnosis of breast lesions since it provides a sufficient amount of tissue to make an accurate histopathological diagnosis. Tumor type & grade are highly correlated with post surgical specimen reports
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