A Prospective Study On Prevalence Of Aerobic Bacteria In Intensive Care Units And Their Antibiotic Susceptibility Pattern In A Tertiary Care Hospital In Jaipur , Rajasthan

Prevalence Of Aerobic Bacteria In Intensive Care

Authors

  • Neha Sharma
  • Dr. Ved Prakash Mamoria
  • Dr. Manisha Jain

Keywords:

infection in icu, antibiogram, antibiotic pattern

Abstract

Introducation: Multi-drug resistant nosocomial infections are one of the leading causes of mortality and
morbidity amongst hospitalized patients throughout the world, accounting a major burden on the patients and public
health system of any country Method :To determine the prevalence of aerobic bacterial in different clinical
specimens received from various Intensive Care Units (MICU, SICU, CCU, PICU, and NICU) and their antibiotic
susceptibility pattern in the isolated organisms in a tertiary care hospital in Jaipur, Rajasthan. Result : Out of 500
samples, 213 (43%) samples showed growth while 287 (57%) did not show any growth. In the 213 positive samples
183 (85.92%) were Gram Negative bacilli while 25(1.74%) were Gram Positive Cocci and 5 (2.34%) were candida
spp.Out of Gram Negative Isolates Acinetobacter Spp. was found to be maximum 35.2% followed by E.coli 19.7% ,
Klebsiella spp.19.2%, Pseudomonas 12.2%, Citrobacter 0.93% and Proteus Spp. 0.93%. Among Gram Positive Isolates
Staphylococcus aureus was maximum 6.5% followed by Enterococcus 3.75%, CONS 0.93% and streptococcus spp.0.
46%. Candida spp. contributes 2.34% of all positive culture. Conclusion: Isolates are sensitive to combination drugs
while more resistant to single drug. Among gram negative bacteria most common isolate was Acinetobacter spp. 75
(35.2%) which were resistant to most of the antibiotics like amoxycillin- clavulanic acid (83%) , cefotaxime (76%),
imipenem (71%), piperacillin- tazobactam (53%),cefepime (57%) while sensitive to aztreonam (64%) and
cotrimoxazole (64%). [Jain MNJIRM2016; 7(2):52-55]

References

1. Richards MJ, Edwards JR, Culver DH, Gaynes RP.
Nosocomial infections in medical intensive care
units in the United States. National Nosocomial
Infections Surveillance System.Crit Care Med
1999;27:887-92.
2. Mulligan ME, Murray, Leisure KA, Ribner BS et al.
Methicillin resistant staphylococcus aureus: A
consensus review of the microbiology, pathogenesis
and epidemiology with implication for prevention
and management. Am J Med 1993; 94: 313-28.
3. Handwerger S, Raucher B, Altarac D, Monka J,
Marchione S, Singh KV et al. Nosocomial outbreak
due to enterococcus faecium highly ressistant to
vancomycin, penicillin and gentamycin. Clin Infect
Dis 1993; 16: 750-55.
4. Shehabi AA, Baadran I.Microbial infection and
antibiotic resistance patterns among Jordanian
intensive care patients. Eastern Mediterranean
Health Journal. 1996: 2(3): 515-520.
5. Wikipedia, Antibiotic Resistance. Wikipedia
Foundation Inc; [Updated 2012 July 29; Cited 2012,
July 30].
6. Yu-Zhi Zhang, Suveer Singh. Antibiotic stewardship
programmes in intensive care units. WJCCM 2015
feb4;4(1):13-28.
7. Vincent JL, Rello J, Marsall J, Silva E, Anzeuto A,
Martin CD, et al. International study of prevalence
and outcomes of infection in intensive care units.
JAMA 2009;302:2323-
8. WHO (April 2014). "Antimicrobial resistance: global
report on surveillance 2014".WHO Retrieved, May
9,2015.
9. Cassir, N; Rolain, JM; Brouqui, P (2014). "A new
strategy to fight antimicrobial resistance: the
revival of old antibiotics.".Frontiers in
10. Ganguly NK, Arora NK, Chandy SJ, Fairoze MN, Gill
JP, Gupta U, et al. Rationalizing Antibiotic use to
limit antibiotic resistance in India. Indian J Med Res
2011;134:281-94.
11. Hi Media Catalogue; Year 2012-13.
12. Livingstone Churchill, Mackie & McCartney Practical
Medical Microbiology,14th edition, New York:
1996.pg no. 97-111, 146,796-800,851-852.
13. Williams Lippincott , Wilkins ,Koneman’s Color Atlas
& Textbook of Diagnostic Microbiology and
Biochemical reactions ,6th edition .Philadelphia
,2006.pg no 946-1014, 1443-1463.
14. . Clinical and Laboratory Standards Institute.
Performance Standards for Antimicrobial Disc Test:
Approved Standards, 9th edition CLSI document M
2-A9, vol. 26 No.1Wayne PA 2006.
15. Mohammadi-mehr M1, Feizabadi MM2
,Antimicrobial resistance pattern of Gram-negative
bacilli isolated from patients at ICUs of Army
hospitals in Iran , Volume 3 Number 1(March 2011)
26-30. IRAN. J. MICROBIOL. 3 (1) : 26-30.
16. Sheth V. Kaushal,Patel K. Tejas, Tripathi C. B.
Antibiotic sensitivity pattern in neonatal intensive
care unit of a tertiary care hospital of india. Asian J
Pharm Clin Res, Vol 5, Issue 3, 2012, 46-50
17. Rubina Sabir , S Faraz Danish Alvi, Asher Fawwad.
Antimicrobial susceptibility pattern of aerobic
microbial isolates in a clinical lab. In Karachi-
Pakistan. Pak. Journal Med Sci. 2013 vol.29. No
3.pg.851-855.
18. Pratiwi wikaningtyas1, Joseph i sigit1, Elin yulinah
sukandar1, Indahwaty gunawan Profile of antibiotic
resistance and usage pattern in icu of private
hospital in bandung, indonesia. International
Journal of Pharmacy and Pharmaceutical Sciences.
ISSN- 0975-1491, Vol 7, Issue 2,2015
19. Zaveri Jitendra R1, Patel Shirishkumar M2, Nayak
Sunil N3, Desai Kanan4, Patel Parul5. A study on
bacteriological profile and drug sensitivity &
resistance pattern of isolates of the patients
admitted in intensive care units of a tertiary care
hospital in Ahmedabad. National Journal of Medical
Research ,Volume 2│Issue 3│July – Sept 2012
20. Maksum Radji1, Siti Fauziah1, Nurgani Aribinuko2
.Asian Pacific Journal of Tropical Biomedicine.
Antibiotic sensitivity pattern of bacterial pathogens
in the intensive care unit of Fatmawati Hospital,
Indonesia. Asian Pac J Trop Biomed 2011; 1(1): 39-
42.

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Published

2018-02-06

How to Cite

Sharma, N., Mamoria, D. V. P., & Jain, D. M. (2018). A Prospective Study On Prevalence Of Aerobic Bacteria In Intensive Care Units And Their Antibiotic Susceptibility Pattern In A Tertiary Care Hospital In Jaipur , Rajasthan: Prevalence Of Aerobic Bacteria In Intensive Care. National Journal of Integrated Research in Medicine, 7(2), 52–55. Retrieved from http://www.nicpd.ac.in/ojs-/index.php/njirm/article/view/1356

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