Prevalence Of Pancytopenia In Patients Of Plasmodium Vivax Malaria In A Tertiary Care Hospital
Prevalence Of Pancytopenia In Patients Of Plasmodium Vivax Malaria
Keywords:
Plasmodium vivax Malaria (P. Vivax), Pancytopenia, Hemophagocytic syndrome (HPS), childrenAbstract
Background &Objective: To study the prevalence of pancytopenia and hemophagocytic syndrome in Plasmodium Vivax infection in pediatric age group. Methods: In all 53 patients presenting during study period with Plasmodium Vivax (P. vivax) malaria and pancytopenia in our institution were evaluated for clinical features, complete hemogram and serum ferritin. Results & Interpretation: Pancytopenia was present in all 53 patients with increase in serum ferritin level in 36 patients. There was significant change noticed in complete blood picture done at admission and on day 7. Conclusions: Pancytopenia and Hemophagocytic syndrome (HPS) were reportedly associated with P. Falciparum infection, though their presence in P. vivax malaria infection was reported only as an isolated case reports. However, this study has found a significant correlation with pancytopenia & HPS in P. Vivax infection as well. Therefore, a high index of suspicion and early treatment is the key to reduce the mortality with this syndrome. [Naveen P NJIRM 2017; 8(1): 21-24]
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